WELCOME
Dear Colleagues and Friends,
As Presidents of both ASPIC and ASEICA, it is a pleasure to invite you to participate at the «II ASPIC-ASEICA International Meeting – Current Trends in Precision Medicine in Cancer» that will take place at 14-15 October, 2021. Given the current Covid-19 situation, this meeting will be done as an online event.
The ASPIC (Portuguese Association for Cancer Research – Associação Portuguesa de Investigação em Cancro; www.aspic.pt) and the ASEICA (Spanish Association for Cancer Research – Asociación Española de Investigación sobre el Cáncer; www.aseica.es) are both members of the European Association for Cancer Research (EACR) and, due to common research interests and geographical proximity, decided to establish a strong network of interactions that include, among other activities, the organization of common international scientific meetings and workshops.
Our main purpose is to disseminate and promote the work developed in both countries and create communication channels and collaboration opportunities among cancer researchers in Portugal and Spain. In addition, we place emphasis on fostering essential connections among basic, clinical and translational cancer researchers.
As a first step towards that direction, ASEICA and ASPIC already co-organized an Immuno-Oncology meeting in 2019, that occurred in Salamanca, that attracted leading researchers working on this topic in Spain, Portugal and other European countries. The organization of this second ASPIC-ASEICA meeting is an additional step towards the consolidation of this connection between the two associations. In this new activity, we expect to attract the participation of scientists working on Precision Medicine in Cancer. The meeting will have 14 invited speakers plus eight talks selected from abstracts sent by attendees.
We invite you then to join us for the II ASPIC-ASEICA International (Virtual) Meeting. We are sure that you will enjoy it!
Joana Paredes (ASPIC President) & Luis Paz-Ares (ASEICA President)
Scientific & Organizing Commitee
Joana Paredes (ASPIC)
Júlio Oliveira (ASPIC)
Carmen Jerónimo (ASPIC)
Bruno Costa (ASPIC)
Luisa Melo (ASPIC)
Luis Paz-Ares (ASEICA)
María S. Soengas (ASEICA)
Xosé Bustelo (ASEICA)
Abstracts Evaluation Committee
Ana Preto (ASPIC)
Bruno Costa-Silva (ASPIC)
Célia Gomes (ASPIC)
Fátima Baltazar (ASPIC)
Sílvia Socorro (ASPIC)
Juan Rodriguez Vita (ASEICA)
Miguel Sanmamed (ASEICA)
Mónica Alvarez (ASEICA)
Patricia González Santamaría (ASEICA)
Toni Celià (ASEICA)
Scientific Programme
Europe/Lisbon ( GMT)
14 October, 2021
9:00h – 9:15h
Official Opening
Luis Costa, ASPIC Past President & Xosé Bustelo, ASEICA Past President
9:15h – 10:00h
Opening Lecture
Chair: Bruno Silva-Santos (IMM, Lisbon, Portugal)
Emergent challenges and opportunities in melanoma treatment
Maria S. Soengas (CNIO, Madrid, Spain)
SESSION 1. Target-based cancer therapies
Chair: Bruno Costa (ICVS, Braga, Portugal)
10:00h – 10:30h
Targeted therapy for primary brain tumors
Michael Weller (University of Zurich, Switzerland)
10:30h – 10:45h
Short Talk 1 – Cracking the ErbB2 sugar code in gastric cancer – a bitter sweet functional target
Henrique O. Duarte (i3S, Porto, Portugal)
10:45h – 11:15h
COFFEE BREAK & POSTER VIEWING
11:15h – 11:45h
Challenges and opportunities for a MYC inhibitor in cancer treatment
Laura Soucek (VHIO, Barcelona, Spain)
11:45h – 12.00h
Short Talk 2 – FGFR inhibition overcomes resistance to EGFR-targeted therapy in epithelial-like cutaneous carcinoma
Purificación Muñoz (IDIBELL, Barcelona, Spain)
12:00h – 12:30h
Patient-derived tumor models for personalized therapeutics in urological cancers
Gabri van der Pluijm (LUMC, Leiden, The Netherlands)
12:30h – 14:00h
LUNCH BREAK & POSTER VIEWING
SESSION 2. Molecular Cancer Biomarkers
Chair : José Carlos Machado (i3S, Porto, Portugal)
14:00h – 14:30h
Susceptibility Genes for Pancreatic Cancer
Nuria Malats (CNIO, Madrid, Spain)
14:30h – 14:45h
Short Talk 3 – Mitochondrial DNA variants oncogenesis and cancer treatment effectiveness
Aurora Gomez-Duran (CSIC, Madrid, Spain)
14:45h – 15:15h
DNA promoter methylation of homologous recombination genes: a predictive biomarker for the responsiveness to PARP inhibitor treatment in testicular germ cell tumors
Carmen Jerónimo (IPO-Porto & ICBAS-UP, Portugal)
15:15h – 15.30h
Short Talk 4 – Deciphering the impact of cancer cell´s secretome and its derived-peptides on breast cancer brain metastasis
Rita Carvalho (i3S, Porto, Portugal)
15:30h – 16:00h
RANKL-RANK in hormone-dependent breast cancer
Sandra Casimiro (IMM, Lisbon, Portugal)
16:00h – 18:00h
Speed Selected Talks
Chairs : Ana Preto (CBMA, U.Minho, Braga, Portugal)
Toni Celià-Terrassa (IMIM, PRBB, Barcelona, Spain)
15 October, 2021
SESSION 3. Novel Cancer Screening Methods
Chair : Sérgio Dias (IMM, Lisbon, Portugal)
9:30h – 10:00h
Uromonitor for the surveillance of non-muscle-invasive bladder cancer patients
Paula Soares (i3S, Porto, Portugal)
10:00h – 10:15h
Short Talk 5 – Inflammatory response of bladder fibroblasts induced by Bacillus Calmette-Guérin-Immunotherapy for non-muscle invasive bladder cancer
Víctor G. Martínez (CIEMAT, Madrid, Spain)
10:15h – 10:45h
Extracellular vesicles in liquid biopsies from cancer patients
EACR SPEAKER – An Hendrix (Ghent University, Ghent, Belgium)
10:45h – 11:15h
COFFEE BREAK & POSTER VIEWING
11:15h – 11.30h
Short Talk 6 – Mapping the biodistribution of endogenously produced pancreatic cancer exosomes
Bárbara Adem (i3S, Porto, Portugal)
11:30h – 12:00h
Zebrafish avatars as a fast screening platform for cancer therapy
Rita Fior (Champalimaud Centre for the Unknown, Champalimaud Foundation, Lisbon, Portugal)
12:00h – 13:30h
LUNCH BREAK & POSTER VIEWING
SESSION 4. Novel Targets for Cancer Therapy
Chair : Júlio Oliveira (IPO-Porto, Portugal)
13:30h – 14:00h
Strategies for moving CAR-T cells for solid tumors into the clinic
Sònia Guedan (IDIBAPS, Barcelona, Spain)
14:00h – 14:15h
Short Talk 7 – Hepatic stellate cells suppress NK cell-sustained breast cancer dormancy
Ana Luísa Correia (FMI, Basel, Switzerland)
14:15h – 14:45h
IL-7R signaling as a therapeutic target in acute lymphoblastic leukemia?
João Barata (IMM, Lisbon, Portugal)
14:45h – 15.00h
Short Talk 8 – Combination of poly(I:C)+resiquimod free or loaded in polymeric nanocapsules reprograms tumor associated macrophages in solid tumors
Fernando Torres Andón (CIMUS, Santiago de Compostela, Spain)
15:00h – 15:30h
Antitumour drugs of Marine Origin
José María Fernández Sousa-Faro (CEO Pharma Mar, Spain)
15:30h – 16:00h
COFFEE BREAK & POSTER VIEWING
16:00h – 16:45h
CLOSING TALK
Chair: Leonor David (Ipatimup & FMUP, Porto, Portugal)
New concepts in precision oncology for breast cancer
Aleix Prat (Medical Oncology, Hospital Clínic de Barcelona, Spain)
16:45h – 17:15h
AWARDS & CLOSING REMARKS
Joana Paredes, ASPIC President, & Luis Paz-Ares, ASEICA President